Page Views: 334 Date Added: 05/20/2010 Last Updated: 05/20/2010 Expiry Date: 05/15/2029 Product/Service Details Common name: tebuconazole IUPAC name: (RS)-1-p-chlorophenyl-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical Abstracts name: (±)-α -[2-(4-chlorophenyl)ethyl]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol Other names: fenetrazole*; terbuconazole*; terbutrazole*; ethyltrianol* CAS RN: [107534-96-3] PHYSICAL CHEMISTRY Composition: Racemate. Mol. wt.: 307.8; M.f.: C16H22ClN3O Form: Colourless crystals; (tech., colourless to light brown powder). M.p.: 105 ºC; V.p.: 1.7x10-3 mPa (20 ºC) (OECD 104). KOW: logP = 3.7 (20 °C). Henry: 1x10-5 Pa m3 mol-1 (20 °C). S.g./density: 1.25 (26 °C). Solubility: In water 36 mg/l (pH 5-9, 20 ºC). In dichloromethane >200, isopropanol, toluene 50-100, hexane 1 y (pH 4-9, 22 °C). See also Environmental Fate. APPLICATIONS Biochemistry: Steroid demethylation (ergosterol biosynthesis) inhibitor. Mode of action: Systemic fungicide with protective, curative, and eradicant action. Rapidly absorbed into the vegetative parts of the plant, with translocation principally acropetally. Uses: As a seed dressing, tebuconazole is effective against various smut and bunt diseases of cereals such as Tilletia spp., Ustilago spp., and Urocystis spp., also against Septoria nodorum (seed-borne), at 1-3 g/dt seed; and Sphacelotheca reiliana in maize, at 7.5 g/dt seed. As a spray, tebuconazole controls numerous pathogens in various crops including: rust species (Puccinia spp.) at 125-250 g/ha, powdery mildew (Erysiphe graminis) at 200-250 g/ha, scald (Rhynchosporium secalis) at 200-312 g/ha, Septoria spp. at 200-250 g/ha, Pyrenophora spp. at 200-312 g/ha, Cochliobolus sativus at 150-200 g/ha, and head scab (Fusarium spp.) at 188-250 g/ha, in cereals; leaf spots (Mycosphaerella spp.) at 125-250 g/ha, leaf rust (Puccinia arachidis) at 125 g/ha, and Sclerotium rolfsii at 200-250 g/ha, in peanuts; black leaf streak (Mycosphaerella fijiensis) at 100 g/ha, in bananas; stem rot (Sclerotinia sclerotiorum) at 250-375 g/ha, Alternaria spp. at 150-250 g/ha, stem canker (Leptosphaeria maculans) at 250 g/ha, and Pyrenopeziza brassicae at 125-250 g/ha, in oilseed rape; blister blight (Exobasidium vexans) at 25 g/ha, in tea; Phakopsora pachyrhizi at 100-150 g/ha, in soya beans; Monilinia spp. at 12.5-18.8 g/100 l, powdery mildew (Podosphaera leucotricha) at 10.0-12.5 g/100 l, Sphaerotheca pannosa at 12.5-18.8 g/100 l, scab (Venturia spp.) at 7.5-10.0 g/100 l, white rot in apples (Botryosphaeria dothidea) at 25 g/100 l, in pome and stone fruit; powdery mildew (Uncinula necator) at 100 g/ha, in grapevines; rust (Hemileia vastatrix) at 125-250 g/ha, berry spot disease (Cercospora coffeicola) at 188-250 g/ha, and American leaf disease (Mycena citricolor) at 125-188 g/ha, in coffee; white rot (Sclerotium cepivorum) at 250-375 g/ha, and purple blotch (Alternaria porri) at 125-250 g/ha, in bulb vegetables; leaf spot (Phaeoisariopsis griseola) at 250 g/ha, in beans; early blight (Alternaria solani) at 150-200 g/ha, in tomatoes and potatoes. Phytotoxicity: Good plant compatibility in most crops with any formulation, and achieved in more sensitive crops by appropriate formulations, e.g. WP, WG or SC. Formulation types DS; EC; ES; EW; FS; GF; SC; SE; WG; WP; WS. MAMMALIAN TOXICOLOGY Oral: Acute oral LD50 for male rats 4000, female rats 1700, mice c. 3000 mg/kg. Skin and eye: Acute percutaneous LD50 for rats >5000 mg/kg. Non-irritating to skin; mild irritant to eyes (rabbits). Inhalation: LC50 (4 h) for rats 0.37 mg/l air (aerosol), >5.1 mg/l (dust). NOEL: (2 y) for rats 300, dogs 100, mice 20 mg/kg diet. ADI: 0.03 mg/kg b.w. Toxicity class: WHO (a.i.) III; EPA (formulation) II ('Elite' 45DF); III ('Folicur' 3.6F) EC hazard: (Xn; R22) ECOTOXICOLOGY Birds: Acute oral LD50 for male Japanese quail 4438, female Japanese quail 2912, bobwhite quail 1988 mg/kg b.w. Dietary LC50 (5 d) for mallard ducks >4816, bobwhite quail >5000 mg/kg feed. Fish: LC50 (96 h) for rainbow trout 4.4, bluegill sunfish 5.7 mg/l (flow through). Daphnia: LC50 (48 h) 4.2 mg/l (flow through). Algae: ErC50 (96 h) for Scenedesmus subspicatus 4.01 mg/l (static). Other aquatic spp.: No effect on Chironomus riparius at 0.1 mg/l (28 d). Bees: LD50 (48 h) (oral) 175.8 ug/bee; (contact) 0.6 ug/bee. Worms: Acute LC50 (14 d) for Eisenia foetida 1381 mg/kg dry soil. Other beneficial spp.: No adverse effects on ground dwellers, e.g. ground beetles (Poecilus cupreus) (adults and larvae) or on foliage dwellers, e.g. ladybirds (Coccinella septempunctata), up to 375 g/ha (EW 250 formulation). ENVIRONMENTAL FATE Animals: After three days, elimination was almost complete (>99%). Tebuconazole was excreted with the urine and the faeces. Plants: Metabolism studies on wheat, grapes and peanuts show that tebuconazole is the major terminal residue. The metabolites detected were mainly triazole-containing compounds of no toxicological relevance. In plant tissue, a mean half-life of 12 days could be derived (cereals). Soil/Environment: The degradation of tebuconazole in soil was slow in laboratory studies. Under field conditions, the compound degraded much more rapidly, and did not accumulate in long-term studies (3-5 y). Since no residues could be detected in deeper soil layers of these and other studies, and adsorption/desorption studies indicated a low mobility in the soil, groundwater contamination through leaching can be excluded. In natural waters, hydrolysis and indirect photolysis occur; in a pond study, the compound dissipated from the water body with DT50 1-4 w. Low vapour pressure and strong adsorption result in low volatilisation into the air.

Tebuconazole

Company Information (Shanghai Skyblue Chemical Co., Ltd.)

Company Profile: Shanghai Skyblue Chemical Co., Ltd. is an integrated company located in Pudong New Area of Shanghai China. Our business scopes include the development, manufacturing, researching, and marketing agrochemicals. We are capable of supplying a wide range of high quality agrochemicals, including insecticides (especially household and public health insecticides), fungicides, herbicides, pesticide synergists and other relative agrochemicals in both technical grade and formulation in different packages as per customer's requirements. To make quality products is our credo. We always target to provide our customers with top quality products along with moderate prices and professional services, and endeavor to be a 360o-solution supplier for agrochemicals. Currently our products are being exported to more than twenty countries and enjoy high reputation in the global market. On the basis of equality and mutual benefits, we always look forward to establishing and maintaining long term partnerships with all customers toward a future of resplendence. At present we can supply the following products: Insecticides: Acetamiprid,Alpha-Cypermethrin, Aluminium Phosphide, Azamethiphos, Beta-Cyfluthrin, Bifenthrin, Bioallethrin, Carbaryl, Carbofuran, Carbosulfan, Cartap, Chlorpyrifos, Cyfluthrin, D-Allethrin, D-Cyphenothrin, Deltamethrin, Dichlorvos, Diethyltoluamide, Dimehypo, Dimethoate, D-Phenothrin, D-Tetramethrin, Empenthrin, Es-bioallethrin, Es-Fenvalerate, Etofenprox, Fenitrothion, Fenpropathrin, Fenthion, Fenvalerate, Fipronil, Flumethrin, Hydramethylnon, Imidacloprid, Imiprothrin, Lambda-cyhalothrin, Malathion, Permethrin, Pirimiphos-methyl, Prallethrin, Propoxur, S-Bioallethrin, Tefluthrin, Tetramethrin, Thiocyclam, Transfluthrin Fungicides: Clofentezine, Difenoconazole, Mancozeb, Metiram, Propiconazole, Propineb, Tebuconazole, Thiabendazole Herbicides: Acetochlor, Ametryn, Atrazine, Bensulfuron-methyl, Butachlor, Chlorimuron-ethyl, Chlorsulfuron, Cyanazine, Fenchlorazole, Fenoxaprop-p-ethyl, Glyphosate, Metsulfuron-methyl, Nicosulfuron, Prometryn, Pyrazosulfuron-ethyl, Quinclorac, Quizalofop-p-ethyl, Simazine, Simetryn, Terbuthylazine, Terbutryn, Tribenuron-methyl Pesticide Synergists: Piperonyl Butoxide, MGK 264. >> More Website URL: http://www.bridgat.com/u15636