Page Views: 276 Date Added: 05/18/2010 Last Updated: 05/18/2010 Expiry Date: 05/13/2029 Product/Service Details Common name: simazine IUPAC name: 6-chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine Chemical Abstracts name: 6-chloro-N,N'-diethyl-1,3,5-triazine-2,4-diamine CAS RN: [122-34-9] PHYSICAL CHEMISTRY Composition: Tech. grade is 97% pure. Mol. wt.: 201.7; M.f.: C7H12ClN5 Form: Colourless powder. M.p.: 225-227 ºC (decomp.) V.p.: 2.94x10-3 mPa (25 ºC) (OECD 104). KOW: logP = 2.1 (25 ºC, unionised). Henry: 5.6x10-5 Pa m3 mol-1 (calc.) S.g./density: 1.33 (22 °C). Solubility: In water 6.2 mg/l (pH 7, 20 ºC). In ethanol 570, acetone 1500, toluene 130, n-octanol 390, n-hexane 3.1 (all in mg/l, 25 ºC). Stability: Relatively stable in neutral, weakly acidic and weakly alkaline media. Rapidly hydrolysed by stronger acids and bases; DT50 (calc.) 8.8 d (pH 1), 96 d (pH 5), 3.7 d (pH 13) (20 °C). Decomposed by u.v. irradiation (c. 90% in 96 h). pKa: 1.62 (20 °C), v. weak base. APPLICATIONS Biochemistry: Photosynthetic electron transport inhibitor at the photosystem II receptor site. Maize tolerance of triazines is attributed to conjugation with glutathione. Mode of action: Selective systemic herbicide, absorbed principally through the roots, but also through the foliage, with translocation acropetally in the xylem, accumulating in the apical meristems and leaves. Uses: Control of most germinating annual grasses and broad-leaved weeds in pome fruit, stone fruit, bush and cane fruit, citrus fruit, vines, strawberries, nuts, olives, pineapples, field beans, french beans, peas, maize, sweet corn, asparagus, hops, alfalfa, lupins, oilseed rape, artichokes, sugar cane, cocoa, coffee, rubber, oil palms, tea, turf and ornamentals. Applied at rates up to 1.5 kg/ha within the EU, and up to 2-3 kg/ha in perennial crops in the tropics and subtropics. Phytotoxicity: Phytotoxic to a number of crops, including sugar beet, tobacco, tomatoes, cucurbits, clover, rice, soya beans, lettuce, oats, and many vegetables (e.g. spinach, onions, carrots, crucifers, etc.). Formulation types: GR; SC; WG; WP. MAMMALIAN TOXICOLOGY Oral: Acute oral LD50 for rats 500-10 000, Chinese hamsters >5000 mg/kg. Skin and eye: Acute percutaneous LD50 for rats >2000 mg/kg. Non-irritating to skin and eyes (rabbits). Inhalation: LC50 (4 h) for rats >5.5 mg/l. NOEL: (2 y) for female rats 0.5 mg/kg b.w. daily; (1 y) for female dogs 0.8 mg/kg b.w. daily; (95 w) for mice 5.7 mg/kg b.w. daily. ADI: 0.005 mg/kg b.w. Toxicity class: WHO (a.i.) III (Table 5); EPA (formulation) IV EC hazard: R40 ECOTOXICOLOGY Birds: Acute oral LD50 for mallard ducks >2000 mg/kg. Dietary LC50 (8 d) for mallard ducks 10 000, Japanese quail >5000 mg/kg. Fish: LC50 (96 h) for bluegill sunfish 90, rainbow trout >100, crucian carp >100, guppies 49 mg/l. Daphnia: LC50 (48 h) >100 mg/l; (21 d) 0.29 mg/l. Algae: EC50 (72 h) for Scenedesmus subspicatus 0.042 mg/l; (5 d) for Selenastrum capricornutum 0.26 mg/l. Bees: LD50 (48 h, oral and topical) >99 ug/bee. Worms: LC50 (14 d) for earthworms >1000 mg/kg. ENVIRONMENTAL FATE Animals: In mammals, following oral administration, 65-97% is eliminated within 24 h as the de-ethylated metabolite. Elimination of low rates is primarily in the urine of rats, with a shift to faecal elimination at high doses. Excretion is rapid (c. 90% in 48 h). Degradation to desethylsimazine and bis-desethylsimazine (diaminochlorotriazine) is the primary metabolic pathway. Plants: Readily metabolised by tolerant plants to the herbicidally-inactive 6-hydroxy analogue and amino acid conjugates. The hydroxysimazine is further degraded by dealkylation of the side-chains and by hydrolysis of the resulting amino groups on the ring, with evolution of CO2. In sensitive plants, unaltered simazine leads to chlorosis and death. Soil/Environment: Major metabolites under all conditions are desethylsimazine and hydroxysimazine. Microbial breakdown in soil results in degradation of simazine at very variable rates; DT50 27-102 d (median 49 d); temperature and soil moisture are the main factors affecting rates. Koc 103-277 (median 160); Kd 0.37-4.66 (12 soils). Under field conditions, simazine has a low leaching potential. Loss by direct photodecomposition is insignificant. Indirect photodecomposition in the presence of photosensitisers such as humic acids is, however, likely.

Simazine, herbicide

Company Information (Shanghai Skyblue Chemical Co., Ltd.)

Company Profile: Shanghai Skyblue Chemical Co., Ltd. is an integrated company located in Pudong New Area of Shanghai China. Our business scopes include the development, manufacturing, researching, and marketing agrochemicals. We are capable of supplying a wide range of high quality agrochemicals, including insecticides (especially household and public health insecticides), fungicides, herbicides, pesticide synergists and other relative agrochemicals in both technical grade and formulation in different packages as per customer's requirements. To make quality products is our credo. We always target to provide our customers with top quality products along with moderate prices and professional services, and endeavor to be a 360o-solution supplier for agrochemicals. Currently our products are being exported to more than twenty countries and enjoy high reputation in the global market. On the basis of equality and mutual benefits, we always look forward to establishing and maintaining long term partnerships with all customers toward a future of resplendence. At present we can supply the following products: Insecticides: Acetamiprid,Alpha-Cypermethrin, Aluminium Phosphide, Azamethiphos, Beta-Cyfluthrin, Bifenthrin, Bioallethrin, Carbaryl, Carbofuran, Carbosulfan, Cartap, Chlorpyrifos, Cyfluthrin, D-Allethrin, D-Cyphenothrin, Deltamethrin, Dichlorvos, Diethyltoluamide, Dimehypo, Dimethoate, D-Phenothrin, D-Tetramethrin, Empenthrin, Es-bioallethrin, Es-Fenvalerate, Etofenprox, Fenitrothion, Fenpropathrin, Fenthion, Fenvalerate, Fipronil, Flumethrin, Hydramethylnon, Imidacloprid, Imiprothrin, Lambda-cyhalothrin, Malathion, Permethrin, Pirimiphos-methyl, Prallethrin, Propoxur, S-Bioallethrin, Tefluthrin, Tetramethrin, Thiocyclam, Transfluthrin Fungicides: Clofentezine, Difenoconazole, Mancozeb, Metiram, Propiconazole, Propineb, Tebuconazole, Thiabendazole Herbicides: Acetochlor, Ametryn, Atrazine, Bensulfuron-methyl, Butachlor, Chlorimuron-ethyl, Chlorsulfuron, Cyanazine, Fenchlorazole, Fenoxaprop-p-ethyl, Glyphosate, Metsulfuron-methyl, Nicosulfuron, Prometryn, Pyrazosulfuron-ethyl, Quinclorac, Quizalofop-p-ethyl, Simazine, Simetryn, Terbuthylazine, Terbutryn, Tribenuron-methyl Pesticide Synergists: Piperonyl Butoxide, MGK 264. >> More Website URL: http://www.bridgat.com/u15636