Page Views: 239 Date Added: 05/20/2010 Last Updated: 05/20/2010 Expiry Date: 05/15/2029 Product/Service Details Common name: malathion; maldison; malathon; mercaptothion; carbofos; mercaptotion IUPAC name: diethyl (dimethoxythiophosphorylthio)succinate; S-1,2-bis(ethoxycarbonyl)ethyl O,O-dimethyl phosphorodithioate Chemical Abstracts name: diethyl [(dimethoxyphosphinothioyl)thio]butanedioate CAS RN: [121-75-5] PHYSICAL CHEMISTRY Composition: Tech. grade is c. 95% pure. Mol. wt.: 330.3; M.f.: C10H19O6PS2; Form: Tech. is a clear, amber liquid. M.p.: 2.85 ºC; B.p.: 156-157 ºC/0.7 mmHg. V.p.: 5.3 mPa (30 ºC). KOW: logP = 2.75; Henry: 1.21x10-2 Pa m3 mol-1 (calc.) S.g./density: 1.23 (25 ºC). Solubility: In water 145 mg/l (25 ºC). Miscible with most organic solvents, e.g. alcohols, esters, ketones, ethers, aromatic hydrocarbons. Slightly soluble in petroleum ether and some types of mineral oil. Stability: Relatively stable in neutral, aqueous media. Decomposed by strong acids and by alkali; hydrolysis DT50 107 d (pH 5), 6 d (pH 7), 0.5 d (pH 9) (all 25 °C). F.p.: 163 °C (Pensky-Martens closed cup). APPLICATIONS Biochemistry: Cholinesterase inhibitor; proinsecticide, activated by metabolic oxidative desulfuration to the corresponding oxon. Mode of action: Non-systemic insecticide and acaricide with contact, stomach, and respiratory action. Uses: Used to control Coleoptera, Diptera, Hemiptera, Hymenoptera and Lepidoptera in a wide range of crops, including cotton, pome, soft and stone fruit, potatoes, rice and vegetables. Used extensively to control major arthropod disease vectors (Culicidae) in public health programmes, ectoparasites (Diptera, Acari, Mallophaga) of cattle, poultry, dogs and cats, human head and body lice (Anoplura), household insects (Diptera, Orthoptera), and for the protection of stored grain. Typical application rates for agricultural uses 0.5-1.25 kg/ha. Phytotoxicity: Non-phytotoxic in general, if used as recommended, but glasshouse cucurbits and beans, certain ornamentals, and some varieties of apple, pear, and grape may be injured. Formulation types: DP; EC; EW; UL; WP. Compatibility: Incompatible with alkaline materials (residual toxicity may be decreased). MAMMALIAN TOXICOLOGY Oral: Acute oral LD50 for rats 1375-5500 mg/kg (pure), mice 775-3320 mg/kg. Skin and eye: Acute percutaneous LD50 (24 h) for rabbits 4100-8800, rats >2000 mg/kg. Inhalation: LC50 (4 h) for rats >5.2 mg/l. NOEL: In 2 y trials on rats, the only effects seen at 500 ppm (29 mg/kg b.w. daily) was inhibition of cholinesterase in plasma and red blood cells. ADI: 0.3 mg/kg b.w. Toxicity class: WHO (a.i.) III; EPA (formulation) III (Fyfanon tech. and 5 EC) EC hazard: Xn; R22 ECOTOXICOLOGY Birds: Dietary LC50 (5 d) for bobwhite quail 3500, ring-necked pheasants 4320 mg/kg diet. Fish: LC50 (96 h) for bluegill sunfish 0.1, largemouth bass 0.28 mg/l. Daphnia: EC50 (48 h) 1.0 ug/l. Algae: EC50 (72 h) 13 mg/l. Bees: Toxic to bees. LD50 (topical) 0.71 ug/bee. Worms: LC50 613 mg/kg soil. ENVIRONMENTAL FATE Animals: In mammals, following oral administration, the major part of the dose is excreted in the urine and faeces within 24 hours. Degradation is by oxidative desulfuration by liver microsomal enzymes, leading to the formation of malaoxon; malathion and malaoxon are hydrolysed and thus detoxified by carboxylesterases. In insects, metabolism involves hydrolysis of the carboxylate and phosphorodithioate esters, and oxidation to malaoxon. Plants: De-esterified to its mono- and di- carboxylic acids, which are cleaved to yield succinic acid, which is subsequently incorporated into plant constituents. Soil/Environment: Under normal conditions, it is 99% degraded by hydrolysis within 7 d.

Malathion

Company Information (Shanghai Skyblue Chemical Co., Ltd.)

Company Profile: Shanghai Skyblue Chemical Co., Ltd. is an integrated company located in Pudong New Area of Shanghai China. Our business scopes include the development, manufacturing, researching, and marketing agrochemicals. We are capable of supplying a wide range of high quality agrochemicals, including insecticides (especially household and public health insecticides), fungicides, herbicides, pesticide synergists and other relative agrochemicals in both technical grade and formulation in different packages as per customer's requirements. To make quality products is our credo. We always target to provide our customers with top quality products along with moderate prices and professional services, and endeavor to be a 360o-solution supplier for agrochemicals. Currently our products are being exported to more than twenty countries and enjoy high reputation in the global market. On the basis of equality and mutual benefits, we always look forward to establishing and maintaining long term partnerships with all customers toward a future of resplendence. At present we can supply the following products: Insecticides: Acetamiprid,Alpha-Cypermethrin, Aluminium Phosphide, Azamethiphos, Beta-Cyfluthrin, Bifenthrin, Bioallethrin, Carbaryl, Carbofuran, Carbosulfan, Cartap, Chlorpyrifos, Cyfluthrin, D-Allethrin, D-Cyphenothrin, Deltamethrin, Dichlorvos, Diethyltoluamide, Dimehypo, Dimethoate, D-Phenothrin, D-Tetramethrin, Empenthrin, Es-bioallethrin, Es-Fenvalerate, Etofenprox, Fenitrothion, Fenpropathrin, Fenthion, Fenvalerate, Fipronil, Flumethrin, Hydramethylnon, Imidacloprid, Imiprothrin, Lambda-cyhalothrin, Malathion, Permethrin, Pirimiphos-methyl, Prallethrin, Propoxur, S-Bioallethrin, Tefluthrin, Tetramethrin, Thiocyclam, Transfluthrin Fungicides: Clofentezine, Difenoconazole, Mancozeb, Metiram, Propiconazole, Propineb, Tebuconazole, Thiabendazole Herbicides: Acetochlor, Ametryn, Atrazine, Bensulfuron-methyl, Butachlor, Chlorimuron-ethyl, Chlorsulfuron, Cyanazine, Fenchlorazole, Fenoxaprop-p-ethyl, Glyphosate, Metsulfuron-methyl, Nicosulfuron, Prometryn, Pyrazosulfuron-ethyl, Quinclorac, Quizalofop-p-ethyl, Simazine, Simetryn, Terbuthylazine, Terbutryn, Tribenuron-methyl Pesticide Synergists: Piperonyl Butoxide, MGK 264. >> More Website URL: http://www.bridgat.com/u15636