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Page Views: 466 Date Added: 11/10/2009 Last Updated: 11/10/2009 Expiry Date: 11/05/2028 Product/Service Details Product name: L-Lysine-S-Carboxy Methyl-L-Cysteine Synonyme: L-Carbocysteine-Lysine, SCMC-Lys CAS#: 49673-81-6 Molecular Formula: C6H14N2O2.C5H9NO4S Specification: Item Specification Description Ivory white or white powder Specific rotation[α]D20 -13.2°~ -15.2° Assay 98.0~101.5% Impurity NMT 0.2% Melting point 178℃~181℃ Moisture 4.0~6.0% IR Meet with the requirements Function: Carbocysteine lysine salt monohydrate (SCMC-Lys) is a well-known mucoactive drug whose therapeutic efficacy is commonly related to the ability of SCMC-Lys to replace fucomucins by sialomucins. The aim of this study was to determine if SCMC-Lys couldexert an anti-oxidant action by scavenging reactive oxygen intermediates (ROIs). Our results show that SCMC-Lys proved effective as a selective scavenger of hypochlorous acid (HOCl) and hydroxyl radical (OH.), this effect being related to the reactivity of the SCMC tioether group. The scavenger activity of SCMC-Lys was observed in free cellular system as well as in activated human polymorphonuclear neutrophils (PMNs). SCMC-Lys scavenger activity on HOCl was paralleled by a powerful protection from HOCl-mediated inactivation ofalpha1-antitripsin (alpha1-AT) inhibitor, the main serum protease inhibitor. Production of interleukin-(IL-)8, a major mediator of PMN recruitment in inflammatory diseases, is known to be mediated by intracellular OH.SCMC-Lys significantly reduced IL-8 production on stimulated human peripheral blood mononuclear cells (PBMCs) in the same range of concentrations affecting OH. activity. It is concluded that SCMC-Lys could exert, in addition to its mucoactive capacity, an anti-oxidant action, thus contributing to the therapeutic efficacy of SCMC-Lys. Additional photos

Company Information (Ningbo Honor Chemtech Co.,Ltd.)

Company Profile: Ningbo Honor Chemtech Co.,Ltd. is a hi-tech share-holding corporation,located in Ningbo, which is a seaport city,in the shore of Donghai Sea. We established in Feb. 2007, and we're mainly producing and dealing with Food ingredients & Nutrition supplements, Feed additives, APIs and Intermediates, Cosmetics, Agricultrual products etc. With the purpose of 'Basing on talent people, Bridging across the technology, Aiming to service for customers, and Cherishing much of quality and honor', we make our best effort to develop ourselves and expand our market share. We export our products mainly to Europe, America, Asia and set up stable marketing channel. Meanwhile, we usually attend to many big-scale abroad exhibitions, in order to enhance the foreign customers' understanding to us, and get more market share. In Nov. 2008, we set up our own factory in Anguo,Hebei province. Our factory mainly produces Ellagic acid, Tea Polyphenols, Lutein, Lycopene, Ginkgo Biloba extract ,Cactus extract,Cinnamon bark extract, Wolfberry extract,Astragalus extract,Hawthorn extract,Artichoke extract, Tribulus Terrestris extract, Echinacea Purpurea extract etc. We have abundant technology and our own self-contained ranks of scientific researchers. Also, we make good cooperation with many chemical institutes and colleges. We can provide the Custom service and development by mandate. Entering into the year 2009, Honor Chemtech made a successful partnership with many famous factory in Amino acids, and jointly developed following products: L-Ornithine L-Aspartate, L-Ornithine HCl, L-Ornithine Acetate, L-Arginine L-Aspartate, L-Arginine Pyroglutamate, DL-Lysine Monohydrate, L-Lysine S-Carboxy Metheyl-L-Cysteine. Otherwise, we also make refining production for some basic Amino Acids: L-Tryptophan, L-Tyrosine, L-Leucine, L-Lysine HCl, L-Lysine Acetate, L-Threonine. Welcome to join us!. >> More Website URL: http://www.bridgat.com/u4040