Page Views: 363 Date Added: 09/30/2011 Last Updated: 09/30/2011 Expiry Date: 11/30/1999 Product/Service Details CDP Choline CAS Number: 987-78-0 Purity: 98% Appearance: white crystalline powder CDP-choline is used in Europe by the brand name Citicoline. Stabilized CDP-Choline (cytidine 5'diphosphocholine) is a naturally occurring, water soluble biological compound that is an essential intermediate for the synthesis of phosphatidylcholine, a major constituent of the grey matter of brain tissue (30%). It is metabolized to yield the free nucleotide cytidine and choline. Scientific research demonstrates that CDP Choline consumption promotes brain metabolism by enhancing the synthesis of acetylcholine, restoring phospholipid content in the brain and regulation of neuronal membrane excitability and osmolarity (by its effect on the ATP-dependent sodium and potassium pumps). Citicoline is a nontoxic intermediate in the biological synthesis of phosphotidylcholine from choline. Studies indicate that Citicoline can increase dopamine receptor densities. In addition, Citicoline induces the increases Adrenocorticotropic hormone (ACTH) levels in a Corticotropin-releasing hormone (CRH) independent manner. Other hormones of the hypothalamic–pituitary–adrenal axis are also increased such as LH, FSH, GH and TSH. Studies conducted on brain cells show that Citicoline can reverse the toxic effects caused by hypoxia, ischemia, and trauma. It is suggested that these neuroprotective properties of Citicoline may involve reinforcement of intracellular glutathione antioxidative system, attenuation of phospholipase A, activation and prevention of phospholipid degradation, and prevention of glutamate neurotoxicity. We also offer Citicoline sodium salt hydrate.

Company Information (Suzhou Tianma Specialty Chemicals Co.,Ltd.)

Company Profile: Suzhou Tianma Pharma is a leading manufacturer of pharmaceutical Intermediates, APIs, peptide related zchemicals and specialty chemicals since established in 1993.The key APIs are Citicoline, Clopidogrel. With a broad range of organic synthesis technologies and bio-technology, Tianma Pharma set up a R&D center and five professional production sites around China. Today we have become a close partner for many multinational chemical companies and leading pharmaceutical companies by providing high quality products from lab scale through pilot trial to commercialized production. Tianma specialty chemicals has been listed in Shenzhen Stock Exchange in July, 2010, with stock code 002453. Nowadays, Tianma has entered into a new era of business development, and will focus more on switching itself from a traditional manufacturer to a more flexible contract service supplier, to comply with our aim to Do whatever it takes to satisfy our customers.. >> More Website URL: http://www.bridgat.com/u46311