Page Views: 235 Date Added: 05/18/2010 Last Updated: 05/18/2010 Expiry Date: 05/13/2029 Product/Service Details Common name: carbofuran IUPAC name: 2,3-dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate Chemical Abstracts name: 2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate CAS RN: [1563-66-2]; (carbofuran phenol [1563-38-8]; 3-ketocarbofuran phenol [17781-16-7]) EEC no.: 216-353-0 PHYSICAL CHEMISTRY Mol. wt.: 221.3; M.f.: C12H15NO3; Form: Colourless crystals. M.p.: 153-154 ºC; (tech. 150-152 ºC); V.p.: 0.031 mPa (20 ºC); 0.072 mPa (25 ºC). KOW: logP = 1.52 (20 ºC); S.g./density: 1.18 (20 ºC). Solubility: In water 320 (20 ºC), 351 (25 °C) (both in mg/l). In dichloromethane >200, isopropanol 20-50, toluene 10-20 (all in g/l, 20 ºC). Stability: Unstable in alkaline media. Stable in acidic and neutral media. Decomposes >150 ºC. DT50 (22 ºC) >1 y (pH 4), 121 d (pH 7), 31 h (pH 9). APPLICATIONS Biochemistry: Cholinesterase inhibitor. Mode of action: Systemic, with predominantly contact and stomach action. Uses: Control of soil-dwelling and foliar-feeding insects (including wireworms, white grubs, millipedes, symphylids, frit flies, bean seed flies, root flies, flea beetles, weevils, sciarid flies, aphids, thrips, etc.) and nematodes in vegetables, ornamentals, beet, maize, sorghum, sunflowers, oilseed rape, potatoes, alfalfa, peanuts, soya beans, sugar cane, rice, cotton, coffee, cucurbits, tobacco, lavender, citrus, vines, strawberries, bananas, mushrooms, and other crops. Formulation types: FS; GR; SC; WP. Compatibility: Incompatible with alkaline materials. MAMMALIAN TOXICOLOGY Oral: Acute oral LD50 for male and female rats c. 8, dogs 15, mice 14.4 mg/kg. Skin and eye: Acute percutaneous LD50 (24 h) for male and female rats >2000 mg/kg; mildly irritating to skin and eyes (rabbits). Inhalation: LC50 (4 h) for male and female rats c. 0.075 mg/l air (aerosol). NOEL: (2 y) for rats and mice 20 mg/kg diet; (1 y) for dogs 10 mg/kg diet. ADI: 0.002 mg/kg b.w. Water GV: 7g/l (based on ADI). Toxicity class: WHO (a.i.) Ib; EPA (formulation) I ('Furadan 4F'), II ('Furadan G') EC hazard: T+; R26/28| N; R50, R53 ECOTOXICOLOGY Birds: Acute oral LD50 for Japanese quail 2.5-5 mg/kg. LC50 for Japanese quail 60-240 mg (as GR5)/kg. Tech.: LC50 0.7-8 mg/kg, depending on species. Fish: LC50 (96 h) for rainbow trout 22-29 mg (as GR5)/l, bluegill sunfish 1.75 mg (as GR3)/l, golden orfe 107-245 mg (as GR5)/l. Tech.: 7.3-362.5 g/l, depending on species. Daphnia: LC50 (48 h) 38.6 g/l. Bees: Toxic to bees (except for granular formulation). ENVIRONMENTAL FATE Animals: Carbofuran is metabolised by hydrolytic and oxidative mechanisms in the rat. At 24 hours after treatment, 72% of the dose was eliminated in the urine, 2% in the faeces, and about 43% of the administered dose was hydrolysed. Over 95% of the material excreted in the urine was in the form of conjugated metabolites. The major metabolite was conjugated 3-ketocarbofuran phenol, while conjugated 3-hydroxycarbofuran was the predominant carbamate metabolite. Both metabolites were also present in the free form. Metabolism of carbamate insecticides is reviewed. Plants: Carbofuran is quickly metabolised into 3-hydroxycarbofuran and ketocarbofuran. Soil/Environment: DT50 in soil c. 30-60 d. Most important metabolite is CO2 formed by microbiological degradation of the phenol compounds. Koc 22.

Carbofuran

Company Information (Shanghai Skyblue Chemical Co., Ltd.)

Company Profile: Shanghai Skyblue Chemical Co., Ltd. is an integrated company located in Pudong New Area of Shanghai China. Our business scopes include the development, manufacturing, researching, and marketing agrochemicals. We are capable of supplying a wide range of high quality agrochemicals, including insecticides (especially household and public health insecticides), fungicides, herbicides, pesticide synergists and other relative agrochemicals in both technical grade and formulation in different packages as per customer's requirements. To make quality products is our credo. We always target to provide our customers with top quality products along with moderate prices and professional services, and endeavor to be a 360o-solution supplier for agrochemicals. Currently our products are being exported to more than twenty countries and enjoy high reputation in the global market. On the basis of equality and mutual benefits, we always look forward to establishing and maintaining long term partnerships with all customers toward a future of resplendence. At present we can supply the following products: Insecticides: Acetamiprid,Alpha-Cypermethrin, Aluminium Phosphide, Azamethiphos, Beta-Cyfluthrin, Bifenthrin, Bioallethrin, Carbaryl, Carbofuran, Carbosulfan, Cartap, Chlorpyrifos, Cyfluthrin, D-Allethrin, D-Cyphenothrin, Deltamethrin, Dichlorvos, Diethyltoluamide, Dimehypo, Dimethoate, D-Phenothrin, D-Tetramethrin, Empenthrin, Es-bioallethrin, Es-Fenvalerate, Etofenprox, Fenitrothion, Fenpropathrin, Fenthion, Fenvalerate, Fipronil, Flumethrin, Hydramethylnon, Imidacloprid, Imiprothrin, Lambda-cyhalothrin, Malathion, Permethrin, Pirimiphos-methyl, Prallethrin, Propoxur, S-Bioallethrin, Tefluthrin, Tetramethrin, Thiocyclam, Transfluthrin Fungicides: Clofentezine, Difenoconazole, Mancozeb, Metiram, Propiconazole, Propineb, Tebuconazole, Thiabendazole Herbicides: Acetochlor, Ametryn, Atrazine, Bensulfuron-methyl, Butachlor, Chlorimuron-ethyl, Chlorsulfuron, Cyanazine, Fenchlorazole, Fenoxaprop-p-ethyl, Glyphosate, Metsulfuron-methyl, Nicosulfuron, Prometryn, Pyrazosulfuron-ethyl, Quinclorac, Quizalofop-p-ethyl, Simazine, Simetryn, Terbuthylazine, Terbutryn, Tribenuron-methyl Pesticide Synergists: Piperonyl Butoxide, MGK 264. >> More Website URL: http://www.bridgat.com/u15636