Page Views: 175 Date Added: 10/25/2011 Last Updated: 10/25/2011 Expiry Date: 10/22/2021 Product/Service Details Product Name Azamethiphos CAS No. 35575-96-3 Categories Insecticides NOMENCLATURE Common name: azamethiphos IUPAC name: S-6-chloro-2,3-dihydro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3-ylmethyl O,O-dimethyl phosphorothioate; 6-chloro-3-dimethoxyphosphinoylthiomethyl-1,3-oxazolo[4,5-b]pyridin-2 (3H)-one Chemical Abstracts name: S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O- dimethyl phosphorothioate EEC no.: 252-626-0 PHYSICAL CHEMISTRY Composition: Tech. is >95%. Mol. wt.: 324.7; M.f.: C9H10ClN2O5PS; Form: Colourless crystals; (tech. is a beige to grey powder). M.p.: 89C. V.p.: 0.0049 mPa (20C). KOW: logP = 1.05; Henry: 1.45x10-6 Pa m3 mol-1 (calc.) S.g./density: 1.60 (20C). Solubility: In water 1.1 g/l (pH 7, 20C). In dichloromethane 610, benzene 130, methanol 100, n- octanol 5.8 (all in g/kg, 20C). Stability: Unstable in acids and alkalis; DT50 (20C) (calc.): 800 h (pH 5), 260 h (pH 7), 4.3 h (pH 9). F.p.: >150C (Marcusson, without stirring). APPLICATIONS Biochemistry: Cholinesterase inhibitor. Mode of action: Insecticide with contact and stomach action. Gives rapid knockdown, and has good residual activity. Uses: Control of flies and other insect pests in animal houses. Control of mosquitoes, tsetse flies, cockroaches, and other public hygiene pests. Formulation types: AE; WP. MAMMALIAN TOXICOLOGY Oral: Acute oral LD50 for rats 1180 mg/kg. Skin and eye: Acute percutaneous LD50 for rats >2150 mg/kg. Mild eye irritant; non- irritating to skin (rabbits). Inhalation: LC50 (4 h) for rats >560 mg/m3 air. NOEL: (90 d) for rats 20 mg/kg diet (2 mg/kg daily), for dogs 10 mg/kg diet (0.3 mg/kg daily). ADI: 0.025 mg/kg. Toxicity class: WHO (a.i.) III; EPA (formulation) III ECOTOXICOLOGY Birds: Acute oral LD50 for bobwhite quail 30.2, mallard ducks 48.4 mg/kg. Dietary LC50 (8 d) for bobwhite quail 860, Japanese quail >1000, mallard ducks 700 ppm. Based on the results of acute laboratory trials, azamethiphos is classified as highly toxic to birds. However, sublethal doses have a repellent effect on birds, so the risk for birds is significantly reduced. Fish: LC50 (96 h) for channel catfish 3, crucian carp 6, guppy 8, rainbow trout 0.115-0.2, sheepshead minnow 2.22 mg/l. Based on the test with the most sensitive species, rainbow trout, azamethiphos is classified as highly toxic to fish. All other test species were less sensitive to this compound. Daphnia: LC50 (48 h) 0.67 ug/l. Bees: Toxic to bees; LD50 (24 h) (oral)

Company Information ( Shanghai Kima Chemical Co., Ltd )

Company Profile: Shanghai Kima Chemical Co., Ltd. is a Chinese leading chemical enterprise and is engaged in the operation of agrochemicals, water treatment chemicals, Silicone sealants, Thickeners and some other chemicals. From the establishment in the year of 2004, the company has become the sole exporting agents for several domestic factories in Jiangsu Province and Zhejiang Province, also become the purchasing windows for many foreign customers. Based on rich operating experience, good occupation manners and strict working attitude, the company has won high reputations from customers. >> More Website URL: http://www.bridgat.com/u14730